Key Characteristics
The Andor BC43 is a compact, benchtop multimodal imaging system. It is an "all-in-one" solution featuring an integrated anti-vibration mechanism and a light-tight lid, allowing it to operate in a standard laboratory environment without the need for a darkroom or an optical table. The BC43 is positioned as a powerful yet accessible instrument that does not require deep microscopy expertise, making it ideal for core facilities. Notably, the system is in-field upgradable, providing a growth path from widefield to confocal and super-resolution imaging to evolve with research needs.
The standout advantages of the BC43 include:
Exceptional Speed & Productivity:
Utilizing microlens spinning disk technology, the BC43 provides instant confocal imaging and captures images at least 10x faster than traditional point-scanning confocals, significantly boosting productivity.It is ideal for imaging fast dynamic events in thicker samples.
Ease of Use & Simplified Workflow:
The system is designed so that even novice users can master it quickly and achieve outstanding results with minimal training.
The workflow is optimized for simplicity: users can add a sample, find the region of interest, and acquire an image without complex setup procedures.
High Image Quality & Flexibility:
The system offers multiple imaging modes in one device: blur-free Confocal, Widefield, Differential Phase Contrast (DPC), and Brightfield.
It is capable of long-term imaging (e.g., 24-hour cell cycle) with no photobleaching or phototoxicity.
The system is "super-resolution ready," capable of revealing subcellular structures beyond the diffraction limit.
Powerful and Integrated Software:
Every BC43 model includes the Imaris Quant package for 2D/3D/4D image visualization, processing, and analysis, including AI-based tools.
The Fusion acquisition software supports real-time, GPU-accelerated deconvolution (ClearView™) and seamless 3D image stitching.
Confocal Technology: Microlens spinning disk.
Core Imaging Modes: Confocal, Widefield epifluorescence, Brightfield, Differential Phase Contrast (DPC).
Fluorescence Illumination: Fixed laser configuration with four wavelengths: 405 nm, 488 nm, 561 nm, 640 nm.
Camera: sCMOS, monochrome.
Resolution: 2040 x 1992 (4.1 MP).
Quantum Efficiency (QE): Up to 82%.
Field of View (FOV): 18.5 mm diagonal.
Bit Depth: 16-bit.
Objectives:
Motorised 5-position nosepiece.
Supports magnifications from 10x to 100x.
Super Resolution: Achievable resolution down to 140-180 nm (sample dependent).
Workstation:
Operating System: Windows™ 11.
Configuration: 64 GB RAM, 512 GB SSD (boot drive), 2 TB (image storage), 16 GB Graphics Card, 27-inch monitor.
