X-ray 3D Microscope ChromaXRM-500

Key Advantages:

Highest Contrast & Highest Throughput for Challenging Samples

The ChromaXRM features Sigray’s patented x-ray multi-color source. Selecting the x-ray color of the x-ray beam illuminating the sample can dramatically improve contrast to visualize details that would otherwise be missed, as clearly is seen in the images below comparing the ChromaXRM to the setup of the next leading XRM. Because of the high contrast, tomographies can be acquired at 10X the throughput for these challenging samples.

500nm Spatial Resolution

ChromaXRM achieves the highest spatial resolution available on the market at 500nm (0.5 µm).
Shown below are individual eggs resolved in the eggs sacks of a daphnia (water flea) specimen.

Multiple Fields of View with 5 Detectors

Up to 5 detector configuration options are available within the same system, enabling selection between multiple resolution and field-of-view settings analogous to a visible light microscope. Below is an example workflow in which detector modes are switched by software to zoom in on features of interest in an intact medicine container.

Life Sciences: Unstained Soft Tissue
X-rays are generally considered too energetic for soft tissue imaging. With the multi-spectral x-ray source on the ChromaXRM, a Chromium target can be selected to provide high quality, cellular resolution imaging of unstained biological soft tissue. Shown is an unstained liver sample with details down to hepatocytes.

 

Carbon Fibers and Low Z Materials
Carbon composites such as carbon fiber reinforced polymers and carbon paper represent some of the most challenging materials for 3D x-ray microscopes to image. The ChromaXRM provides excellent contrast and resolution for these samples, which enable straightforward segmentation for quantification.

Silicon carbide composite using the ChromaXRM. Contrast is substantially improved in comparison with W-based x-ray source results
 

Pharmaceuticals
Microstructural imaging during process development is critical in minimizing time to market. ChromaXRM provides the ability to: quantify batch to batch variations in coating thickness, measure the distribution of API in formulation, and find cracks, voids and defects in tablets and pills. Choice of x-ray target in Sigray’s patented multi-spectral x-ray source improves contrast and throughput.

Entomology and Botany


Selection of lower x-ray energies on the ChromaXRM’s multi-spectral contrast source enables excellent contrast for imaging insects and plants for entomology and botany research.

Technical Specifications of the ChromaXRM-500

 ParameterSpecification
OverallSpatial Resolution0.5 um with 40X objective
Minimum Voxel275 nm
SourceTypeSigray patented ultrahigh brightness sealed microfocus source
Voltage20 - 60 kVp
Power100W
Target(s)Up to 5 targets.
Includes selection from Cr, Cu, Rh, W, Mo, Au, Ti, Ag.
Others available upon request.
Detector(s)TypeUp to 5 detectors. Includes LFOV detectors and high resolution detectors.
Camera4MP deep cooled CCD
Visible Light Camera16MP alignment camera
SoftwareCommand and ControlSigray 3D with Intuitive interface
ReconstructionGigaRecon - fastest commercial CBCT reconstruction software
Offset ScansExpands the horizontal FOV. Sigray software advantage
Helical ScanEnabled for tall samples
AutoPilotAI-assisted microscope operation for unsupervised acquisition
Linux WorkstationInterface is on a Windows workstation, while a separate robust Linux workstation controls the system. Advantageous for reliable 24-7 operation.
EPICSOpen-source software controls for maximum flexibility
DimensionsFootprintDesktop system
250 kg
Sample Size50 x 50 mm diameter
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